DMSO is a cryoprotectant that can penetrate cell membranes and protect cells from damage during freezing and thawing.
DMSO is thought to prevent the formation of ice crystals by increasing the intracellular solute concentration, thereby promoting the vitrification of water at low temperatures.
Product Name:Dimethyl Sulfoxide
Alias:Dimethyl Sulphoxide
EC:200-664-3
CAS:67-68-5
MF:C2H6OS
MW:78.13g/mol
Colorless clear liquid or solid
Melting point: 66.2°F (19°C)
Boiling point: 372.2°F (189°C)
Density: 1.10 g/cm³C
Specification:
| Items | Specifications | ||
| I | II | III | |
| Appearance | Transparent liquid or crystallize | Transparent liquid or crystallize | Transparent liquid or crystallize |
| Purity(BY GC) | 99.98Min | 99.96Min | 99.90Min |
| Crystallization point ℃ | 18.3Min | 18.3Min | 18.1Min |
| Transparency(400nm) | 99Min | 99Min | 98Min |
| Acid Value(mg KOH/g) | 0.01Max | 0.02Max | 0.03Max |
| Refractive Index(20℃) | 1.4778-1.4800 | 1.4778-1.4800 | 1.4775-1.4800 |
| Water | 0.03%Max | 0.03%Max | 0.1%Max |
| Density(25℃ g/cm³) | 1.0940-1.1030 | 1.0940-1.1030 | 1.0940-1.1030 |
| Chroma(Hazen) | 10Max | 10Max | 10Max |
In histology and cytology, DMSO is used to prepare tissue samples for microscopic examination. Adding dimethyl sulfoxide to proprietary plastic polymer–paraffin blends can shorten infiltration time and facilitate the production of thin sections.
In solid-phase peptide synthesis, DMSO is used as a reaction solvent for the coupling between resin-bound fragments and activated carboxyl groups on incoming fragments.
DMSO is widely used to dissolve proteins and peptides for purification by preparative HPLC in reverse-phase mode.
